As a Professor of Immunology and Director of the Biotherapy Department at the Pitié‐Salpêtrière hospital and Pierre and Marie Curie medical school, my main activities are to develop translational research in Immunology. I built-up a global organization – research unit and hospital department – that is one of the rare structure capable of developing biotherapies from bench to bedside. My main research activities are focused on regulatory T cells (Tregs) and I have recently pioneered the development of IL2 as a Treg stimulator (Saadoun D, et al., N Engl J Med, 2011 and Hartemann A, et al. Lancet E&D 2013).