Peripheral blood inflammatory autoimmune phenotypes indicate immunological heterogeneity in type 1 diabetes and high risk unaffected siblings (#64)

5:05 PM

Sefina Arif

T-cell autoreactivity at onset of pediatric Type 1 Diabetes (T1D) is related to adiposity but not autoantibodies nor c-peptide (#66)

5:05 PM

Dorothy J Becker

CD4⁺Tm cells in children with T1D and their siblings show increased sensitivity to activation induced cell death (#67)

5:05 PM

Michael L Bian

Superoxide Production Mediates Anti-Viral Responses to Diabetogenic Viruses (#68)

5:05 PM

Ashley R Burg

Insulitis in type 1 diabetes (#69)

5:05 PM

Martha Campbell-Thompson

  Assessing insulin-specific T-cell tolerance in the NOD mouse model tolerant to proinsulin (#70)

5:05 PM

Jonathan Chee

  Effector-Memory T-Cells develop in islets and report islet pathology in Type 1 diabetes (#71)

5:05 PM

Jonathan Chee

An Integrated Approach to Determine ZnT8-specific T Cell Repertoire in Type 1 Diabetes Patients and Healthy Adults (#72)

5:05 PM

Daisuke Chujo

Expression of innate immunity genes and damage of primary human pancreatic islets by epidemic strains of echovirus: Implication for post-virus islet autoimmunity. (#73)

5:05 PM

Corrado M M Cilio

Association of FOXP3 Polymorphisms with GAD65 Autoantibodies in Type 1 Diabetes  (#74)

5:05 PM

Corrado M Cilio

Temporal changes in cytokine expression following coxsackievirus infection of human islets (#75)

5:05 PM

Maria Craig

Avidity-dependent programing of autoreactive T cells in type 1 diabetes (#76)

5:05 PM

Ivana Durinovic-Bello

Investigating the relevance of enterovirus-specific CD8 T cell immunity in Type 1 diabetes (#77)

5:05 PM

Martin Eichmann

Late detection of latent autoimmune diabetes in adults associated with lower GAD antibody concentration (#78)

5:05 PM

Spiros Fourlanos

Low expression level of Peripheral CD4+PD-1+T-cells in Japanese Patients with Type 1A Diabetes (#79)

5:05 PM

Reiko Fujisawa

Latent Autoimmune Diabetes of Adults (LADA): Islet-related Autoimmunity Identifies a Unique Pattern of Impaired Beta -Cell Function and Pathology. (#80)

5:05 PM

Roberto Gianani

Beta cell mass in islet autoantibodies positive organ donors. (#81)

5:05 PM

Roberto Gianani

Increased Th22 cells are independently associated with Th17 cells in type 1 diabetes (#82)

5:05 PM

Yong Gu

Efficient mail-based sampling for Type 1 diabetes (T1D) autoantibody surveillance (#83)

5:05 PM

William Hagopian

Genetic control of regulatory T cell function in Type 1 diabetes (#84)

5:05 PM

Emma E Hamilton-Williams

Rapid assays for detection of type 1 diabetes associated autoantibodies in organ donors (#85)

5:05 PM

Taina Härkönen

  Rotavirus infection causes pancreatic apoptosis, ß-cell dysfunction and transient hyperglycemia (#86)

5:05 PM

Margo C Honeyman

Interferon-gamma expressing Th17 cells appear late in the development of Type 1 Diabetes (#87)

5:05 PM

Jarno Honkanen

Coxsackievirus B1 is associated with type 1 diabetes – results from virus antibody survey in different European populations (#88)

5:05 PM

Heikki Hyoty

Variable associations of non-HLA risk loci with different phases of the autoimmune process in type 1 diabetes (#89)

5:05 PM

Jorma Ilonen

Novel Enzyme-Linked Immunosorbent Assay for Bivalent ZnT8 Autoantibodies (#90)

5:05 PM

Eiji Kawasaki

A Simple Dipstick Assay Based on Lateral Flow Separation for the detection of islet antigen 2 (IA-2) autoantibodies in human serum samples (#91)

5:05 PM

Ingrid Kikkas

Effects of dietary gluten on murine Natural Killer cell activity  (#92)

5:05 PM

Jesper Larsen

Preclinical evaluation of efficacy and safety of a new vaccine against Coxsackievirus B1 – Implications for type 1 diabetes development (#93)

5:05 PM

Pär Larsson

Gestational infections affects birth weight differently in smoking and non-smoking mothers: The Environmental Determinants of Diabetes in the Young (TEDDY) study. (#94)

5:05 PM

Åke Lernmark

Elevation of serum levels of transglutaminase antibody in patients with autoimmune thyroid diseases and autoimmune diabetes (#95)

5:05 PM

Yu Liu

Clinical Trial of Ustekinumab for the treatment of T1D. (#96)

5:05 PM

Ashish K Marwaha

Ljungan virus antibody validation and relation to islet autoantibodies in autoimmune ( type 1) diabetes patients and controls. (#97)

5:05 PM

Anna-Lena Nilsson

Early infant feeding and islet autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study (#98)

5:05 PM

Jill M. Norris

Vitamin D Metabolism Genes Associated with Development of Early Childhood Islet Autoimmunity and Diabetes:  The TEDDY Study  (#99)

5:05 PM

Jill M. Norris

A search for susceptibility genes contributing to islet-specific autoimmunity in type 1 diabetes by association studies with multiple autoimmune diseases (#100)

5:05 PM

Shinsuke Noso

A lower frequency of insulin peptide B9-23-reactive IL-10-producing cells observed in type 1 diabetic patients with HLA-DRB1*09:01. (#101)

5:05 PM

Yoichi Oikawa

Ablation of reactive oxygen species intensifies diabetogenic CD4 T cell effector responses (#102)

5:05 PM

Lindsey E Padgett

Rhesus monkey rotavirus outer capsid protein VP7 confers on a bovine rotavirus the ability to replicate more efficiently in mice, elevate rotavirus-specific T helper 1-biased antibody responses and accelerate diabetes onset (#103)

5:05 PM

Jessica A Pane

TCR repertoire and antigen-specificity of human islet-infiltrating CD8⁺ T cells (#105)

5:05 PM

Vimukthi Pathiraja

Analysis of the repertoire of insulin-reactive CD8⁺ T cells (#106)

5:05 PM

James A Pearson

Non-synonymous Single Nucleotide Polymorphisms (SNPs) in the IA-2 Gene and Novel Epitopes within the IA-2 Extracellular Domain (#107)

5:05 PM

Massimo Pietropaolo

Inhibition of NADPH-oxidase (NOX) derived superoxide in T cells maintains Sirtuin-1 (Sirt-1) activity, oxidative phosphorylation, and T cell hyporesponsiveness. (#108)

5:05 PM

Jon D. Piganelli

Systematic Evaluation Of Genes Associated With Type 1 Diabetes Susceptibility (#109)

5:05 PM

Ramesh Ram

Soluble CD52 suppresses innate immune responses and is a candidate therapeutic agent in type 1 diabetes (#110)

5:05 PM

Maryam Rashidi

Spatial distribution of islet-associated leukocytes and beta cell nitrosative stress as contributors to beta cell loss in type 1 diabetes: studies in a cohort of nPOD cases (#111)

5:05 PM

SHIVA REDDY

Homozygosity of the HLA-DRB1*03,DQB1*0201 or DRB1*04,DQB1*0302 haplotypes increases the metabolic severity of T1D onset. (#112)

5:05 PM

Arleta Rewers

Increased weight or height gain in infants/toddlers does not predict early development of T1D: The Environmental Determinants of Diabetes in the Young (TEDDY) Study  (#113)

5:05 PM

Marian Rewers

CD8 infiltration of the exocrine pancreas is a common pathological feature of human type 1 and type 2 diabetes (#114)

5:05 PM

Teresa Rodriguez-Calvo

MHC-I hyperexpression correlates with the presence of the enteroviral capsid protein VP1 both in the islets and in the exocrine pancreas. (#115)

5:05 PM

Teresa Rodriguez-Calvo

Characterization of insulin specific autoreactive CD8+ T cells in autoimmune diabetes (#116)

5:05 PM

NARESH SACHDEVA

IL-10 receptor and endoplasmic reticulum stress impairs STAT3 activation in type 1 diabetes patients and their healthy first degree relatives (#117)

5:05 PM

Mamdouh Sedhom

Higher frequency of CD25-CD4+ cells observed in type 1 diabetes with HLA A*24:01 (#118)

5:05 PM

Akira Shimada

Role of IL-22 producing Th17 cells in Type 1 diabetes (#119)

5:05 PM

Bhagirath Singh

NPY minor autoantibodies in newly diagnosed type 1 diabetes patients. (#120)

5:05 PM

Hanna Skärstrand

Epitope specificity and affinity determined with recombinant ZnT8-aa275-369 variant proteins in specific ZnT8R and ZnT8W autoantibody positive type 1 diabetes patients  (#121)

5:05 PM

Hanna Skärstrand

Novel Insights into the Molecular Mechanisms by which Enteroviruses Impair Insulin-Secretion  (#122)

5:05 PM

Emma Svedin

Islet Antibody Remission and Risk of Type 1 diabetes in Very Young Patients in the TEDDY Study (#123)

5:05 PM

Kendra Vehik

The Six-year Incidence of Diabetes Associated Autoantibodies in the Genetically At-risk: The TEDDY Study (#124)

5:05 PM

Kendra Vehik

Th1/Th2/Th17/Treg cytokines expression levels in the peripheral blood of type 1 and type 2 diabetes patients (#125)

5:05 PM

JIAN WANG

Changes in zinc transporter 8 autoantibodies post onset: Studies from the Type I Diabetes Genetics Consortium. (#126)

5:05 PM

Janet M Wenzlau

Proliferating germinal centres are decreased in recent onset type 1 diabetes pancreatic lymph nodes (#127)

5:05 PM

Abby Willcox

Autoantibodies to GAD(96-585) identify GAD autoantibody positive relatives of patients with type 1 diabetes at increased risk of diabetes progression (#128)

5:05 PM

Alistair JK Williams

The important role of MyD88 in dendritic cells in obesity and metabolic syndrome (#129)

5:05 PM

Yufei Xiang

Inhibition of increased circulating Tfh cell by anti-CD20 monoclonal antibody in patients with type 1 diabetes (#130)

5:05 PM

Xinyu Xu

T cells specific for Insulin B:11-23 restricted on HLA-DQ8 are frequently detected in T1D patients and primarily recognize Register 3 as the immunogenic peptide binding mode on DQ8 (#131)

5:05 PM

Junbao Yang

A negative association between HLA-A*24 and islet autoantibody responses in pre-diabetes (#132)

5:05 PM

Jody Ye

Higher prediction values of ECL-IAA and -GADA assays for type 1 diabetes (#133)

5:05 PM

Liping Yu

Low prevalence of GAD and IA2 antibodies in Indian patients with type 2 diabetes: a clinic and community based study (#134)

5:05 PM

Eesh Bhatia